Розлекс парацетамол пользуется большим спросом среди покупателей. Кажется, что это средство хорошо изучено потребителями. Но это не так. Как любое лекарственное средство розлекс парацетамол имеет свои специфические особенности. Прочитав эту статью, можно подробно изучить данный препарат.
- Форма выпуска и состав
- Фармакодинамика
- Фармакокинетика
- Описание и свойства препарата
- Показания к применению
- Побочные действия
- Противопоказания
- Взаимодействие с другими лекарственными средствами
- Способ применения и дозы
- Особые указания
- Передозировка
- Условия хранения
- Срок хранения
- Отзывы о препарате парацетамол розлекс
Форма выпуска и состав
В одном флаконе находится 50 миллилитров вещества. В 100 миллилитрах сиропа находится 2,4 грамма действующего вещества.
Фармакодинамика
Розлекс парацетамол включает в себя следующие свойства:
- Как жаропонижающие
- Обладает слабым противовоспалительным свойством
- Действует как анальгетик
- Понижает температуру тела;
- Также блокирует вещества, способствующие образованию воспалительных процессов;
Благодаря этим свойством розлекс парацетамол пользуется большим спросом.
Фармакокинетика
После употребления средства, происходит распространение вещества по организму и причем очень стремительно. В основном метаболизм средства происходит в желудочно-кишечном тракте. Если было употреблена оптимальная доза (500 мг), то достигает крови от десяти до шестидесяти минут и его концентрация будет равна 6 миллиграмм на миллилитр, а примерно через шесть часов 12 микрограмм на миллилитр. Розлекс парацетамол распространяется по всему телу, кроме жировой ткани и спином мозгу.
Связь между средством и белками >10%, а с сульфатными метаболитами связи практически нет. Полный распад происходит благодаря печени, с помощью окисления, в котором участвуют вещества, выделяемые печенью и цитохром. Метаболит под названием гидроксилированный, который отрицательно влияет на организм, образуется путем реакции организма на розлекс парацетамола. Далее может произойти реакция (детоксификация с глютатионом), из-за которой происходит накаливание (обычно при передозировке), при которой повреждаются мягкие ткани.
Такие конъюгированные метаболиты как глюкурованная и серная кислота, не являются биологически активными веществами. Поэтому розлекс взаимодействует именно с ними. У детей, которые родились недоношенными (до одного года), преобладает сульфатный метаболит.
Период частичного вывода вещества из организма составляет около трех часов, а у людей, страдающих циррозом печени, несколько больше. Полное очищение тканей почек от парацетамола розлекс составляет около пяти процентов. Вывод из организма осуществляется с мочой. Остальная часть ( >5%) выводится в неизменном виде.
Описание и свойства препарата
Сироп обладает жаропонижающим и противовоспалительным свойством. Также действует как анальгетик. Хранится в флаконах, разных по количеству вещества.
Показания к применению
Если есть чувство слабой или умеренной боли. Такими являются мигрень, головная боль, менструальная боль, боль в полости рта, при боли, вызванной различными травмами, такими как ожог, перелом. Также прописывается при инфекционных заболеваниях, сопровождаемые воспалением, такие как лихорадка.
Побочные действия
При приеме данного препарата побочные эффекты проявляются редко, но все же они есть.
Побочные действия в желудочно-кишечном тракте: нарушение пищеварения, а если принимать долго и в высоких дозах, тогда возможно отравление печени.
Побочные эффекты для крови: образование тромбоцитопения, лейкопении, арганулоцитоза и других заболеваний.
Со стороны аллергии возможно образование сыпи на кожи, ощущение зуда.
Противопоказания
Розлекс парацетамол, как и препарат Медисорб, противопоказан если человек страдает хроническим алкоголизмом или у него присутствует повышенная чувствительность к самому лекарству.
Взаимодействие с другими лекарственными средствами
Если применять препарат одновременно с антикоагулянтами, то может появится длительное и выраженное протромбиновое время. Если с антихолинергическими средствами, то метаболизм разлекса парацетамола замедлится.
Если применять розлекс парацетамол и одновременно пероральные контрацептивы, то метаболизм препарата ускоряется, а его действие как анальгетика уменьшается. Если применять с урикозурическими средствами, то действия этих средств, становятся неактивны. Если употреблять с активированным улем, то биодоступность обоих уменьшится. Если применять вместе с диазепамом, то его время выведения заметно увеличится.
Возможны случаи, когда при применении зивовудина с сиропом, увеличивался миелодепрессивный эффект, а также может случится тяжелое токсичное поражение печени. Также действие будет возможно токсично в том случае, если употреблять его с изониазидом. Возможен прием с Кагоцелом.
Остальные взаимодействия препаратов с парацетамолом розлекс, менее важны и часты.
Способ применения и дозы
Важно перед употреблением знать способ применения. Обычно, лекарственный препарат принято применять после еды, по истечении двух часов, при этом запивая водой. Применяется около трех раз в день.
«Внимание, для установки курса и его длительности, необходимо поговорить с лечащим врачом».
Для точности дозирования сиропа, можно воспользоваться чайной ложкой. В одной чайной ложке около 120 миллиграмм препарата. Дозы по возрастам распределяются так:
- Дозы для детей (2-6 лет): от пяти до десяти миллилитров сиропа;
- Дети 6-12 лет: от десяти до двадцати миллилитров;
- Взрослые и дети от 12 лет: от двадцати до сорока миллилитров;
Обычно курс лечения составляет: три дня как жаропонижающие и пять дней как анальгетик. «Важно, если вы решили продлить курс приема, то необходимо получить разрешения у лечащего врача».
Особые указания
С различными заболеваниями печени, а также для людей пожилого возраста, прием и дозы лекарства индивидуальны.
Также если срок приема длителен, необходимо сдавать анализы для контроля периферии крови, а также функций печени.
Передозировка
При неправильном употреблении количества лекарства может быть вызвана передозировка. Ее симптомами являются: бледность, боль в области живота, тошнота и рвота (первые сутки). По истечении суток наблюдается повреждение печени и почек (возможна почечная недостаточность, при которой грозит летальный исход или кома).
«Внимание, если выявлены симптомы передозировки, необходимо немедленно показаться врачу».
Условия хранения
Хранить в темном, недоступном солнечным лучам и детям месте. Не допускать воздействию температуры +30° С и не допускать заморозки сиропа.
Срок хранения
Срок хранения данного препарата составляет три года, после того, как продукт был изготовлен.
Отзывы о препарате парацетамол розлекс
О препарате парацетамол розлекс пишут следующие отзывы:
Виктория,33 года, Нижний Новгород: До определенного времени не использовала данное лекарство в качестве сиропа, пока не наткнулась на него в интернете. Приобрела, всё устроило! Отличное средство.
Ксения, 29 лет, Самара: Долгое время использую данный препарат. Довольна его действием и ни разу не было побочных действий.
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